Acidosis (or Tissue Acid Waste) in Muscle Tissues Causes Local and Referred Pain
Acidic Buffer Induced Muscle Pain Evokes Referred Pain and Mechanical Hyperalgesia in Humans
Overview – Repeat studies have shown that acidosis (tissue acid waste in body) has multiple negative effects. It is “well known that some diseased areas, such as cancer nests, inflammation loci (localized inflammation) and infarction areas (heart or other organs that have had the blood supply cut off) are acidified”. Gene Expressions for Signal Transduction under Acidic Conditions, i PMCID: PMC3899954
Additional research has also noted – “The existence and apparent redundancy of multiple pH surveillance systems attests to the concept that acid–base regulation is a vital issue for cell and tissue homeostasis.
Up-regulation and over activity of acid sensors appear to contribute to various forms of chronic pain. . . . “ Handbook of Experimental Pharmacology Volume 194, 2009, pp 283-332, 10 Jun 2009
Acidosis is taking center stage when it comes to many of the afflictions humans are suffering from. As you will see in this peer- reviewed published paper, it can be the main cause for myofacial, trigger point, fibromyalgia and chronic pain.
This research provides substantial evidence that not only can centralized acidosis in muscle causes localized pain but also referred pain.
I have provided a shortened version of this PubMed paper so that you can get the initial details of the finding of this study. I have also provided a link to the complete study online.
My Conclusion
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Authors Frey Law Laura A,1 Sluka Kathleen A,1 McMullen Tara,1 Lee Jennifer,1 Arendt-Nielsen Lars,2 and Graven-Nielsen Thomas2
Keywords: Fibromyalgia, Myofascitis, Chronic Fatigue Syndrome, Hyperalgesia, Chronic Pain, Trigger Points, Myalgia
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